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4th International Conference on Cardiovascular Diseases and Therapeutics

Prague, Czech Republic

Haniye Ghasemof Juyomi

Haniye Ghasemof Juyomi

Shiraz University of Medical Sciences, Iran

Title: The Effects of Combine Oral Contraceptive Pills on Cardiovascular Risk Factors: A Systematic Review on Clinical Trials


Biography: Haniye Ghasemof Juyomi


Background: The combine contraceptive pills (COCPs), included a combination of esterogen and progesterone, are an accepted therapeutic for pregnancy prevention. Several studies indicated that  COCP intake might have some side effects, such as cardiovascular diseases (CVD). Therefore this study aimed to investigate  the effects of COCP on CVD risk factors. 

Methods: Google Scholar, PubMed and Magiran Library databases were systematically searched to find relevant clinical trials investigating the effects of COCPs on CVD from inception up to June 2020.

Results: Included articles (n = 10) assessed several risk factors such as blood pressure, serum levels of total cholesterol, triglyceride, low-density lipoprotein (LDL) and  high-density lipoprotein (HDL). A total of the articles indicated the increament of blood pressure, serum levels of cholesterol, triglyceride, LDL and reduction in HDL following COCPs intake.

Conclusions: The results of studies showed that COCP intake for long time is related to the increase of the CVD risk factors and most  probably they have an adverse effects on cardiovascular disease.

Keyword: Contraceptive Pills, Cardiovascular Disease, Lipid profile