Scientific Program

Conference Series LLC Ltd invites all the participants across the globe to attend International Conference on Cardiovascular Diseases and Therapeutics | Paris, France

Venue: Holiday Inn Paris - Marne la Vallée

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Day 1 :

Keynote Forum

Dr. Ehud Baron

CTO, X-Cardio Corp. KK, Japan

Keynote: While you were sleeping- night cardiology health maps
CVDT 2018 International Conference Keynote Speaker Dr. Ehud Baron photo
Biography:

Ehud Baron, MD D.Sc, is the chairman and president of X-Cardio Corp. KK, Tokyo, Japan, Concardio, Inc., Cleveland, OH, and GoldTech Sino, Ltd., HK and Shenzhen, China. On Years 1975 to 1995, I served as university professor and researcher in Tubingen University, Germany, Aalborg University, Institute of Electronics Systems, Denmark, Zurich Kanton Spital and Bazel Hoffman La Roche, Switzerland, in the Technion - Israel Inst. of Technology in Medical Faculty and Bio-Medical Engineering faculty, UC Berkeley and Stanford University. During this academic period research topics included physiological models for muscle motor units, working on sleep inducing medication and automatic sleep stages, Parkinsonian tremor and motion signal analysis, and cerebral blood flow. At this days I was fortunate to be one of the pioneers in AI and Machine learning based Healthcare, both at UC Berkeley using Fuzzy sets and fuzzy control and at Stanford University working on back propagation Neural Networks algorithms for cerebral blood flow and motion signals analysis. After crossing the lines to the Industrial part of AI in Health care, I founded and ran several AI start Ups using machine learning for cardiology models. on 2009 I got a grant from GCIC, Cleveland Clinic to develop non invasive, Cuffless and Continuous estimation of hemodynamics. The device that was developed for Critical Care in CCU and during operations, has been further converted to a wearable device, a bracelet and later a wireless ring that measures continuously BP and Cardiac Output 24 h, during daily life. This reflects my believe in promoting medicine that is continuous 24h 365 days a year, is non obtrusive and provides a Health Space where each patient or healthy person can see their position in the Health space, their target zone and alternative paths to the target which represent different interventions or treatment.

Abstract:

The Problem: In order to appreciate the meaning of Hypertension beyond BP numeric value, we can employ 24H unobtrusive monitoring of cardiovascular health to assess progress or deterioration, and produce 24H BP graphs and Personal Health Maps (PHM)

 

Methodology: We suggest PHM for each patient to provide at a glance the position of the patient on the Health Space at any given time. It is based on Fuzzy sets, where each patient get different level of membership in different pathological and healthy conditions. The PHM shows the patient’s Pulse Shape trace during the night and condition can be assessed in one glance. In one study in Calcutta hospital, 30 hypertensive and diabetic patients were monitored at home 24H both with ABPM recording their BP every 15 min and continuous PPG that was used to predicted BP and Cardiac Output continuously. In a second clinical trial we compared our Hemodynamics prediction to Continuous Hemodynamics CNAP device, during Hemodialysis in Fresenius Kidney Center, in St. Louis hospital. Using 2-4 light wavelengths allowed us also to interrogate the capillary bed at different penetration levels to estimate features related to the microcirculation.

 

Findings: We did Fuzzy clustering by an algorithm we developed to cluster the pulse shapes in the feature space. We discovered that different health conditions fell into different clusters.

 

Conclusions & Significance: The finding that different health condition can be defined by the BP pulse shape clustering, generates a continuous Health space. Cluster centroids that represent various pulse shape belong to different health conditions. This provides a powerful tool to see patients progress or deterioration in a quantitative way that also indicates the way for more effective interventions. It is only the very beginning but first finding look quite promising. This can solve the problem of cardiology at night time, or how to detect deterioration in early stage in an unobtrusive and automatic way during night watch.

 

Keynote Forum

Dr. Sandeep Shah

CEO, Tarilian Laser Technologies and ViCardio & Senior Clinical Fellow, The Barts Heart Centre, UK

Keynote: A dynamic new world order for digital blood pressure measurement: Introduction to Tarilian laser technologies

Time : 11:05-11:50

CVDT 2018 International Conference Keynote Speaker Dr. Sandeep Shah photo
Biography:

Dr Sandeep Shah is a leading pioneer in the Medtech Industry and a Medical Doctor, an international Medical Technology Development Expert with sector expertise in technology transfer, regulation, clinical research, market adoption and business development. He is an expert on blood pressure measurement and haemodynamics. Sandeep is Co-Founder and CEO of Tarilian Laser Technologies and ViCardio® Ltd, which has developed an award-winning patented powerful cuffless non-invasive solution to blood pressure measurement and haemodynamics.

Sandeep has previously served as a Global Medical Director and Strategic Advisor to a number of Medtech companies and has a strong knowledge and expertise in technical and commercial development, as well as research in the medical technology field. Sandeep was a founder member of the Medical Devices (IPAC) committee of the National Institute for Clinical Excellence; and also Founder & Past Editor of the MedTech Business Review, a leading publication in the Industry which he initiated and developed; as well lead Advisor to The Medtech Investing Conference Series. Furthermore, Sandeep has established 5 leading University Post-graduate Medtech Programmes in Biomedical Engineering and also within MBA programmes. Sandeep is also a Senior Clinical Research Fellow at the Departments of Cardiology and Clinical Pharmacology, The Barts Heart Centre, London. Sandeep is a graduate of The Royal London and Barts Medical Colleges and Imperial College University.

 

Abstract:

Tarilian Laser Technologies (TLT) is an innovative Medtech Company based in Welwyn Garden City, Hertfordshire & Leeds and also Minneapolis, Minnesota, USA. Our main clinical centre is The Barts Heart Centre in London, Europe’s largest cardiovascular research centre. At TLT, we have developed a novel optical platform technology based on our internal proprietary patented opto-electronic micro-sensor for full haemodynamic profiling including our ability to generate beat to beat blood pressure, compliance data, cardiac output and regional blood flow and blood pressure. A unique aspect of the TLT Sapphire sensor is that no energy enters the body at all – hence, it is truly non-invasive and does not require any compression/cuff and nor any calibration. The sensor is simply applied onto the body and it works instantly delivering continuous beat to beat haemodynamic data. The technology has already won many international awards and TLT has over 47 issued patents. TLT is finalizing its manufacturing translation programme for market launch. The TLT technology is set to revolutionize blood pressure measurement and cardiology, including in the community, hospital ward and OPD and critical care; and also, the emerging consumer wearable markets. An additional interest is the ability of our technology to measure regional/localized blood pressure and flow: including central retinal, renal arterial, maternal and fetal and placental blood pressure and flow. TLT has also commenced major programme of research on blood pressure variability and novel carotid applications especially in relation to the carotid body and sinus. The author will present the data from the pivotal study comparing the TLT technology performance to that of the intra-arterial line (IABP) at The Barts Heart Centre ICU.

 

Keynote Forum

Dr. Nita Shah

CTO, Tarilian Laser Technologies and ViCardio, UK

Keynote: The future horizons for development of digital products for the cardiovascular sector & the impact of machine learning

Time : 11:50-12:35

CVDT 2018 International Conference Keynote Speaker Dr. Nita Shah photo
Biography:

Nita Shah is a global thought-leader and Inventor in the Medtech Industry, with significant Medtech Engineering expertise and also is a Molecular Biologist and Virologist. Nita is an expert on medical device engineering and product development.

Nita is Co-Founder and CTO of Tarilian Laser Technologies and ViCardio® Ltd, which has developed an award-winning patented powerful cuffless non-invasive solution to blood pressure measurement and haemodynamics.

Nita leads all of TLT’s Engineering and Technical Teams, Group Manufacturing & Quality Management Systems Programmes, Co-leads the Intellectual Property Programmes and is in charge of Strategic Management of TLT and Vicardio MedTech projects.

Nita has additional qualifications in Medical Law and is also a trained Classical Indian Dancer as well as being a leading scientist. She is a graduate of Queen Mary and Brunel University, London.

Nita has been recognised by the Bloomberg  Network as a key female entrepreneur and global leader in The Medtech Industry.

Abstract:

The author will describe the exciting new modern world of digital Medtech development – the future significance of digital products and their disruption of modern day cardiovascular medical and surgical management through novel sensing platforms. She will expand on future horizons in biometric sensing in cardiology– the opportunities, challenges and likely impacts on clinical care pathways. The author will also describe the journey of development of Tarilian Laser Technologies (TLT) – which is an innovative Medtech Company based in Welwyn Garden City, Hertfordshire and Leeds and also Minneapolis, Minnesota, USA; with its main clinical center being at The Barts Heart Centre in London, Europe’s largest cardiovascular research center. TLT have developed a novel optical platform technology based on its internal proprietary patented opto-electronic micro-sensor for full hemodynamic profiling including our ability to generate beat to beat blood pressure, compliance data, cardiac output and regional blood flow and blood pressure. She will also describe the modern world of rapid product development and prototyping, how to engage doctors, nurses and patients in product design and development, and how the industry is going through a new revolution through the impact of Artificial Intelligence Systems.